Tangential Flow Filtration: Getting Concentration and Diafiltration Right

At a glance. Tangential flow filtration concentrates proteins, vaccines and vectors while small molecules and buffer pass through the membrane. The Tech Inc. TFF and Diafiltration System controls transmembrane pressure and adds buffer automatically.

Features that protect the product

• Low-shear pumps for sensitive proteins and viral vectors.

• Constant TMP or constant flux control to avoid gel layers.

• Automatic diafiltration to an exact number of volumes.

• Sanitary or single-use flow path for cleanability.

Scale-up

Use the same cassette format and loading from lab to pilot, so production runs follow the development recipe.

Frequently asked questions

Cassettes or hollow fibres? Both can be fitted.

What area do we need? Lab systems start at 0.1 m²; process-development systems go to 2.5 m².

Contact mail@techincresearch.com to size a system.